Lasheen, Deena S.

deenalasheen@pharma.asu.edu.eg
Interests: Medicinal Chemistry and Drug Discovery,
Internal ID: rp12112
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Full Name
Lasheen, Deena S.
 
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Publications

Results 21-29 of 29 (Search time: 0.0 seconds).

Issue DateTitleAuthor(s)
21Aug-2020Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitorsHadi, Soha R Abd El; Soliman, Dalia H; Elrazaz, Eman ; Khaled A M Abouzid ; Lasheen, Deena S. 
2226-Aug-2020Elaborating piperazinyl-furopyrimidine based scaffolds as phosphoinositol-3-kinase enzyme alpha (PI3Kα) inhibitors to combat pancreatic cancerMansour, Mai A; Lasheen, Deena S. ; Gaber, Hatem M; Khaled A M Abouzid 
235-Oct-2021Novel benzenesulfonamides aryl and arylsulfone conjugates adopting tail/dual tail approaches: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studiesEldeeb, Assem H; Abo-Ashour, Mahmoud F; Angeli, Andrea; Bonardi, Alessandro; Elrazaz, Eman ; Nocentini, Alessio; Gratteri, Paola; Abdel-Aziz, Hatem A; Supuran, Claudiu T; Lasheen, Deena S. 
248-Mar-2022Identification of novel furo[2,3-d]pyrimidine based chalcones as potent anti-breast cancer agents: synthesis, in vitro and in vivo biological evaluationMansour, Mai A; Oraby, Mamdouh A; Muhammad, Zeinab A; Lasheen, Deena ; Gaber, Hatem M; Khaled A M Abouzid 
25Dec-2022Design, synthesis, and biological evaluation of new thieno[2,3-d] pyrimidine derivatives as targeted therapy for PI3K with molecular modelling studyElmenier, Fatma M; Lasheen, Deena ; Abouzid, Khaled 
26Dec-2022Molecular design, synthesis and biological evaluation of novel 1,2,5-trisubstituted benzimidazole derivatives as cytotoxic agents endowed with ABCB1 inhibitory action to overcome multidrug resistance in cancer cellsAbdelhafiz, Abeer H A; Lasheen, Deena S. ; Wang, Nessa; Sobeh, Mansour; Wink, Michael; Abouzid, Khaled ; Serya, Rabah 
272023Design, Molecular Modelling and Synthesis of Novel Benzothiazole Derivatives as BCL-2 inhibitorsIsmail, Hoda S.; Khalil, Amira; Taha, Rabah A.; Lasheen, Deena S. ; Abou El Ella, Dalal 
281-Dec-2024Targeting apoptosis; design, synthesis and biological evaluation of new benzoxazole and thiazole based derivativesShahin, Mai I. ; Samir, Nermin; Lasheen, Deena S. ; Ella, Dalal A.Abou El; Helmy, Sama 
29Oct-2025Design, synthesis and biological evaluation of triazolo[1,5-a]pyrimidine derivatives as new antiproliferative agents with multikinase inhibitory activityEldeeb, Assem H; Shahin, Mai I. ; Jaballah, Maiy Y; Elaraby, Ahmed R; Ibrahim, Tamer M; Elaasser, Mahmoud M; Abdel-Aziz, Hatem A; Lasheen, Deena S. ; Abou El Ella, Dalal A