Evaluation of MicroRNA-210 and Protein tyrosine phosphatase, non-receptor type 2 in Pre-eclampsia
Adel, S.; Mansour, A.; Louka, M.; Matboli, M.; Elmekkawi, S.F.; Swelam, N.;
Abstract
The precise origin of Pre-eclampsia (PE) remains elusive. Multiple pieces of evidence support the existence of hypoxia in PE. MiRNA-210 (miR-210), which is induced by Hypoxia-Inducible Factor-1α (HIF-1α) during hypoxia, is one of the most hypoxia sensitive miRNAs. MiR-210 mediates these functions by regulating a lot of target mRNAs. Protein tyrosine phosphatase, non-receptor type 2 (PTPN2) was one of miR-210 targets and was found to be down regulated by hypoxia.
Other data
| Title | Evaluation of MicroRNA-210 and Protein tyrosine phosphatase, non-receptor type 2 in Pre-eclampsia | Authors | Adel, S. ; Mansour, A. ; Louka, M. ; Matboli, M. ; Elmekkawi, S.F. ; Swelam, N. | Issue Date | 2017 | Journal | Gene | DOI | 105-109 http://www.scopus.com/inward/record.url?eid=2-s2.0-84994246885&partnerID=MN8TOARS 596 1879-0038 10.1016/j.gene.2016.10.014 |
PubMed ID | 27746364 | Scopus ID | 2-s2.0-84994246885 |
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