Hekal, Mohamed H.

mohamed.hekal@sci.asu.edu.eg

Interests: Synthetic organic chemistry, Design and synthesis of molecules having unique biological activity, In vitro anticancer evaluation,
Internal ID: rp11457
  • 169 Scopus Citations
  • 2 PubMed Citations

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mohamed.hekal@sci.asu.edu.eg
 
 
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Hekal, Mohamed H.
 
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Publications

Results 1-20 of 32 (Search time: 0.0 seconds).

Issue DateTitleAuthor(s)
12026New Pyrazole-Based Compounds as Potential Multi-Kinase Inhibitors with Antiproliferative Activity: Synthesis, In Vitro Biological Evaluation, and In Silico StudiesSamir, Sandy S; Abdel-Megid, Mohamed; Salem, Mostafa E; Hekal, Mohamed H. ; Ali, Yasmeen M; Alzahrani, Abdullah YA; Rafat, El-Hady
22026Transformation of 3-(4-methoxybenzylidine)-5-(p-tolyl)-2(3H)-furanone into new nitrogen heterocyclic candidates as insecticidal agents with in silico studiesGad, Nourhan M.; Haneen, David S. A.; Hosni, Eslam M.; Hekal, Mohamed H. ; Abdalha, Abdelaal A.; Sayed Karam Ramadan Emam ; Wael Abou-Elmagd 
331-Jul-2025Synthesis and in silico studies of new thiophene-isoquinolinone hybrids as potential larvicides against Culex pipiensMohamed Abo Elhoda Darwish ; Hekal, Mohamed H. ; El-Azm, Fatma S. M. Abu ; Hosni, Eslam M; Ali, Yasmeen M; Yahya Abdullah Alzahrani, Abdullah; Rafat, El-Hady
42025Synthesis, biological evaluation, and in silico studies of new pyrrolone derivatives as potent antiproliferative agentsHekal, Mohamed H. ; El-Azm, Fatma SM Abu; Samir, Sandy S; Alzahrani, Abdullah YA; Ali, Yasmeen M
518-Oct-2024Rational design and synthesis of new pyrrolone candidates as prospective insecticidal agents against Culex pipiens L. LarvaeHekal, Mohamed H. ; El-Azm, Fatma S. M. Abu ; Abdel-Haleem, Doaa R; Rafat, El-Hady; Ali, Yasmeen M; Hashem, Ahmed 
617-Jul-2024Synthesis, DFT Calculations, and Biological Studies of New 2-cyano-3-(naphthalene-1-yl)acryloyl amide Analogues as Anticancer AgentsHekal, Mohamed H. ; Abdalha, Abdelaal A; Farag, Hanaa; Mohamed, Amira T A
73-Jan-2024New pyrazolo[3,4-d]pyrimidine derivatives as EGFR-TK inhibitors: design, green synthesis, potential anti-proliferative activity and P-glycoprotein inhibitionHassaballah, Aya I; AboulMagd, Asmaa M; Hemdan, Magdy M. ; Hekal, Mohamed H. ; El-Sayed, Amira A; Farag, Paula S
81-Jan-2024Novel pyrano[2,3-c]pyrazolopyrimidines as promising anticancer agents: Design, synthesis, and cell cycle arrest of HepG2 cells at S phaseHaneen, David S.A.; Hekal, Mohamed H. ; El-Sayed, Wael ; Wael Abou-Elmagd 
92-Aug-2021An efficient synthesis and evaluation of some novel quinazolinone-pyrazole hybrids as potential antiproliferative agentsAbdelaal A. Abdalha ; Mohamed Hussein Hussein Moustafa Hekal 
1016-Jul-2021New N-(1,3,4-thiadiazol-2-yl)furan-2-carboxamide derivatives as potential inhibitors of the VEGFR-2Soliman Farag Saad, Paula ; Hemdan, Magdy M. ; El-Sayed, Wael ; Mohamed Hussein Hussein Moustafa Hekal 
112021An efficient approach for the synthesis and antimicrobial evaluation of some new benzocoumarins and related compoundsMohamed Hussein Hussein Moustafa Hekal ; Abu El-Azm, Fatma ; Samir, SS
122021New Benzochromeno[2,3-d]Pyrimidines and Benzochromenotriazolo[1,5-c]Pyrimidines as Potential Inhibitors of Topoisomerase IISamir, SS; Ali, YM; El-Sayed, Wael ; Hekal, Mohamed H. 
13Jun-2020Synthesis of new oxadiazol-phthalazin derivatives with anti-proliferative activity; molecular docking, pro-Apoptotic, and enzyme inhibition profileEl-Sayed, Wael ; El-Naggar AM; Abu El-Azm, Fatma ; Mohamed Hekal 
142020Utilization of cyanoacetohydrazide and 2-(1,3-dioxoisoindolin-2-yl) acetyl chloride in the synthesis of some novel anti-proliferative heterocyclic compoundsMohamed Hekal ; Ali, Yasmeen M.; Abu El-Azm, Fatma 
1519-Oct-2019Convenient synthesis and anti-proliferative activity of some benzochromenes and chromenotriazolopyrimidines under classical methods and phase transfer catalysisAmira T. Ali; Mohamed Hekal 
169-Jul-2019Ecofriendly and highly efficient microwaveinduced synthesis of novel quinazolinone-undecyl hybrids with in vitro antitumor activitySaad R. Atta-Allah; Abu El-Azm, Fatma ; Hekal, Mohamed H. 
172019Facile Synthesis and Anticancer Activity of Novel 4-Aminothieno[2,3-d]pyrimidines and TriazolothienopyrimidinesAli, Amira T.; Hekal, Mohamed H. ; Abu El-Azm, Fatma 
182019N'-(1-([1,1'-biphenyl]-4-yl)ethylidene)-2-cyanoacetohydrazide as scaffold for the synthesis of diverse heterocyclic compounds as prospective antitumor and antimicrobial activitiesHamed, Nancy A.; Marzouk, Magda I.; Hekal, Mohamed H. ; Ismail, Mahmoud 
192019Design, Synthesis, and Evaluation of Some Novel Heterocycles Bearing Pyrazole Moiety as Potential Anticancer AgentsAbdelgawad, Nancy; Hekal, Mohamed H. ; Marzouk, Magda I.; Ismail, Mahmoud 
202019Synthesis, Spectral Characterization, and In Vitro Biological Evaluation of Some Novel Isoquinolinone‐based Heterocycles as Potential Antitumor AgentsMohamed Hekal ; Abu El-Azm, Fatma ; Hanan Sallam